The Board of Directors is the Foundation's highest management and decision-making body and is made up of the founders and patrons, currently comprising 7 (seven) members.
The Manhiça Foundation, as described in the Articles of Association, has as its founders:

• The Mozambican State;

• The National Institute of Health;

• The Kingdom of Spain;

• The Fundació Clinic per la Recerca Biomédica (The Fundació Clinic per la Recerca Biomédica, by resolution of the Board of Patrons on 14 November 2014, renounced all its rights as a founding member, including its participation in the Foundation's governing bodies).

• Dr. Pascoal Mocumbi is an Honorary Founder due to his relevant contribution to the formation of the Foundation.

Patrons are individuals or legal entities, without restriction on number, who express an interest in contributing to the achievement of the Foundation's purposes, through a written proposal from the candidate, signed by a Founding Member and approved by the Board of Directors.

Patrons will be included in the honorary or associate categories.

• The Eduardo Mondlane University , the Foundation for Community Development and the Barcelona Institute for Global Health (ISGlobal) are associated patrons due to their contribution to the execution of the Foundation's activities.

• Prof. Pedro Luis Alonso is an honorary patron due to his contribution to promoting the development of the Foundation.

They are bodies of the Foundation

• The Board of Directors;

• The Executive Committee;

• The Scientific Council;

• The Supervisory Board.